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A conserved viral amphipathic helix governs the replication site-specific membrane association

Positive-strand RNA viruses assemble their viral replication complexes (VRCs) on specific host organelle membranes, yet it is unclear how viral replication proteins recognize and what motifs or domains in viral replication proteins determine their destinations. We show here that an amphipathic helix...

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Detalles Bibliográficos
Autores principales: Sathanantham, Preethi, Zhao, Wenhao, He, Guijuan, Murray, Austin, Fenech, Emma, Diaz, Arturo, Schuldiner, Maya, Wang, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9473614/
https://www.ncbi.nlm.nih.gov/pubmed/36048900
http://dx.doi.org/10.1371/journal.ppat.1010752