Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human monocytes/macrophages

The evolutionarily successful poxviruses possess effective and diverse strategies to circumvent or overcome host defense mechanisms. Poxviruses encode many immunoregulatory proteins to evade host immunity to establish a productive infection and have unique means of inhibiting DNA sensing-dependent t...

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Detalles Bibliográficos
Autores principales: Conrad, Steven J., Raza, Tahseen, Peterson, Erich A., Liem, Jason, Connor, Richard, Nounamo, Bernice, Cannon, Martin, Liu, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9473615/
https://www.ncbi.nlm.nih.gov/pubmed/36103568
http://dx.doi.org/10.1371/journal.ppat.1010316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9473615/
https://www.ncbi.nlm.nih.gov/pubmed/36103568
http://dx.doi.org/10.1371/journal.ppat.1010316

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