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A combined spectroscopic and molecular modeling Study on structure-function-dynamics under chemical modification: Alpha-chymotrypsin with formalin preservative

Enzyme function can be altered via modification of its amino acid residues, side chains and large-scale domain modifications. Herein, we have addressed the role of residue modification in catalytic activity and molecular recognition of an enzyme alpha-chymotrypsin (CHT) in presence of a covalent cro...

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Detalles Bibliográficos
Autores principales: Biswas, Pritam, Adhikari, Aniruddha, Pal, Uttam, Mondal, Susmita, Mukherjee, Dipanjan, Ghosh, Ria, Obaid, Rami J., Moussa, Ziad, Choudhury, Sudeshna Shyam, Ahmed, Saleh A., Das, Ranjan, Pal, Samir Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9473634/
https://www.ncbi.nlm.nih.gov/pubmed/36118312
http://dx.doi.org/10.3389/fchem.2022.978668