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Chronic neurotransmission increases the susceptibility of lateral-line hair cells to ototoxic insults

Sensory hair cells receive near constant stimulation by omnipresent auditory and vestibular stimuli. To detect and encode these stimuli, hair cells require steady ATP production, which can be accompanied by a buildup of mitochondrial byproducts called reactive oxygen species (ROS). ROS buildup is th...

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Detalles Bibliográficos
Autores principales: Lukasz, Daria, Beirl, Alisha, Kindt, Katie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9473691/
https://www.ncbi.nlm.nih.gov/pubmed/36047587
http://dx.doi.org/10.7554/eLife.77775