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ONSET-1 Phase 2b Randomized Trial to Evaluate the Safety and Efficacy of OC-01 (Varenicline Solution) Nasal Spray on Signs and Symptoms of Dry Eye Disease

The purpose of this trial was to evaluate the safety and efficacy of OC-01 (varenicline solution), a nicotinic acetylcholine receptor agonist nasal spray, on signs and symptoms of dry eye disease. METHODS: A phase 2b, multicenter, randomized, double-masked, vehicle-controlled trial (ONSET-1; NCT0363...

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Detalles Bibliográficos
Autores principales: Wirta, David, Torkildsen, Gail L., Boehmer, Blair, Hollander, David A., Bendert, Edward, Zeng, Lijuan, Ackermann, Michael, Nau, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cornea 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9473713/
https://www.ncbi.nlm.nih.gov/pubmed/36107843
http://dx.doi.org/10.1097/ICO.0000000000002941