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Baicalein Induces Apoptosis of Rheumatoid Arthritis Synovial Fibroblasts through Inactivation of the PI3K/Akt/mTOR Pathway

PURPOSE: Rheumatoid arthritis (RA) shows abnormal proliferation, apoptosis, and invasion in fibroblast-like synoviocytes (FLSs). Baicalein (BAI), extracted from Scutellaria baicalensis, is used as an anticancer drug through inducing cancer cells apoptosis. However, the mechanism of BAI in RA progres...

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Detalles Bibliográficos
Autores principales: Zhang, Xue, Guan, Xia, Piao, Yingshi, Che, Xiangguo, Si, Mengge, Jin, Jingchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9473868/
https://www.ncbi.nlm.nih.gov/pubmed/36118088
http://dx.doi.org/10.1155/2022/3643265