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A targeted metabolomics method for extra- and intracellular metabolite quantification covering the complete monolignol and lignan synthesis pathway

Microbial synthesis of monolignols and lignans from simple substrates is a promising alternative to plant extraction. Bottlenecks and byproduct formation during heterologous production require targeted metabolomics tools for pathway optimization. In contrast to available fractional methods, we estab...

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Detalles Bibliográficos
Autores principales: Steinmann, Andrea, Schullehner, Katrin, Kohl, Anna, Dickmeis, Christina, Finger, Maurice, Hubmann, Georg, Jach, Guido, Commandeur, Ulrich, Girhard, Marco, Urlacher, Vlada B., Lütz, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474286/
https://www.ncbi.nlm.nih.gov/pubmed/36119807
http://dx.doi.org/10.1016/j.mec.2022.e00205