Early stages of misfolding of PAP248-286 at two different pH values: An insight from molecular dynamics simulations

PAP248-286 peptides, which are highly abundant in human semen, aggregate and form amyloid fibrils that enhance HIV infection. Previous experimental studies have shown that the infection-promoting activity of PAP248-286 begins to increase well before amyloid formation takes place and that pH plays a...

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Detalles Bibliográficos
Autores principales: Agrawal, Nikhil, Parisini, Emilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474323/
https://www.ncbi.nlm.nih.gov/pubmed/36147683
http://dx.doi.org/10.1016/j.csbj.2022.08.060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474323/
https://www.ncbi.nlm.nih.gov/pubmed/36147683
http://dx.doi.org/10.1016/j.csbj.2022.08.060

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