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Early stages of misfolding of PAP248-286 at two different pH values: An insight from molecular dynamics simulations
PAP248-286 peptides, which are highly abundant in human semen, aggregate and form amyloid fibrils that enhance HIV infection. Previous experimental studies have shown that the infection-promoting activity of PAP248-286 begins to increase well before amyloid formation takes place and that pH plays a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474323/ https://www.ncbi.nlm.nih.gov/pubmed/36147683 http://dx.doi.org/10.1016/j.csbj.2022.08.060 |