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Dendritic cell-mimicking scaffolds for ex vivo T cell expansion

We propose an ex vivo T cell expansion system that mimics natural antigen-presenting cells (APCs) for adoptive cell therapy (ACT). Microfiber scaffolds coated with dendritic cell (DC) membrane replicate physicochemical properties of dendritic cells specific for T cell activation such as rapid recogn...

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Detalles Bibliográficos
Autores principales: Kim, Hye Sung, Ho, Tzu-Chieh, Willner, Moshe J., Becker, Michael W., Kim, Hae-Won, Leong, Kam W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474324/
https://www.ncbi.nlm.nih.gov/pubmed/36157246
http://dx.doi.org/10.1016/j.bioactmat.2022.08.015