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Dendritic cell-mimicking scaffolds for ex vivo T cell expansion
We propose an ex vivo T cell expansion system that mimics natural antigen-presenting cells (APCs) for adoptive cell therapy (ACT). Microfiber scaffolds coated with dendritic cell (DC) membrane replicate physicochemical properties of dendritic cells specific for T cell activation such as rapid recogn...
Autores principales: | Kim, Hye Sung, Ho, Tzu-Chieh, Willner, Moshe J., Becker, Michael W., Kim, Hae-Won, Leong, Kam W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474324/ https://www.ncbi.nlm.nih.gov/pubmed/36157246 http://dx.doi.org/10.1016/j.bioactmat.2022.08.015 |
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