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Anchoring geometry is a significant factor in determining the direction of kinesin-14 motility on microtubules

Kinesin-14 microtubule-based motors have an N-terminal tail attaching the catalytic core to its load and usually move towards microtubule minus ends, whilst most other kinesins have a C-terminal tail and move towards plus ends. Loss of conserved sequences external to the motor domain causes kinesin-...

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Detalles Bibliográficos
Autores principales: Yamagishi, Masahiko, Sumiyoshi, Rieko, Drummond, Douglas R., Yajima, Junichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474454/
https://www.ncbi.nlm.nih.gov/pubmed/36104376
http://dx.doi.org/10.1038/s41598-022-19589-4