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Anchoring geometry is a significant factor in determining the direction of kinesin-14 motility on microtubules
Kinesin-14 microtubule-based motors have an N-terminal tail attaching the catalytic core to its load and usually move towards microtubule minus ends, whilst most other kinesins have a C-terminal tail and move towards plus ends. Loss of conserved sequences external to the motor domain causes kinesin-...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474454/ https://www.ncbi.nlm.nih.gov/pubmed/36104376 http://dx.doi.org/10.1038/s41598-022-19589-4 |