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Determination of pharmacokinetics and tissue distribution of a novel lutetium-labeled PSMA-targeted ligand, (177)Lu-DOTA-PSMA-GUL, in rats by using LC–MS/MS

Prostate specific membrane antigen (PSMA) is known to be overexpressed in prostate cancer cells, providing as a diagnostic and therapeutic target for prostate cancer. A lutetium-labeled PSMA targeted ligand, (177)Lu-DOTA-PSMA-GUL is a novel radiopharmaceutical, which has been developed for the treat...

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Detalles Bibliográficos
Autores principales: Song, Chang Ho, Kim, Kweon, Kang, Eunhee, Jeong, Bora, Lee, Myung-Su, Jung, Jiyoon, Kim, Tae Hwan, Shin, Soyoung, Shin, Beom Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474474/
https://www.ncbi.nlm.nih.gov/pubmed/36104447
http://dx.doi.org/10.1038/s41598-022-19700-9