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Streptococcus agalactiae cadD alleviates metal stress and promotes intracellular survival in macrophages and ascending infection during pregnancy

Perinatal infection with Streptococcus agalactiae, or Group B Streptococcus (GBS), is associated with preterm birth, neonatal sepsis, and stillbirth. Here, we study the interactions of GBS with macrophages, essential sentinel immune cells that defend the gravid reproductive tract. Transcriptional an...

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Detalles Bibliográficos
Autores principales: Korir, Michelle L., Doster, Ryan S., Lu, Jacky, Guevara, Miriam A., Spicer, Sabrina K., Moore, Rebecca E., Francis, Jamisha D., Rogers, Lisa M., Haley, Kathryn P., Blackman, Amondrea, Noble, Kristen N., Eastman, Alison J., Williams, Janice A., Damo, Steven M., Boyd, Kelli L., Townsend, Steven D., Henrique Serezani, C., Aronoff, David M., Manning, Shannon D., Gaddy, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474517/
https://www.ncbi.nlm.nih.gov/pubmed/36104331
http://dx.doi.org/10.1038/s41467-022-32916-7