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Cephem‐Pyrazinoic Acid Conjugates: Circumventing Resistance in Mycobacterium tuberculosis
Tuberculosis (TB) is a leading source of infectious disease mortality globally. Antibiotic‐resistant strains comprise an estimated 10 % of new TB cases and present an urgent need for novel therapeutics. β‐lactam antibiotics have traditionally been ineffective against M. tuberculosis (Mtb), the causa...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474573/ https://www.ncbi.nlm.nih.gov/pubmed/35697660 http://dx.doi.org/10.1002/chem.202200995 |