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Confined migration induces heterochromatin formation and alters chromatin accessibility
During migration, cells often squeeze through small constrictions, requiring extensive deformation. We hypothesized that nuclear deformation associated with such confined migration could alter chromatin organization and function. By studying cells migrating through microfluidic devices that mimic in...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474860/ https://www.ncbi.nlm.nih.gov/pubmed/36117991 http://dx.doi.org/10.1016/j.isci.2022.104978 |