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Multiple parameters shape the 3D chromatin structure of single nuclei at the doc locus in Drosophila

The spatial organization of chromatin at the scale of topologically associating domains (TADs) and below displays large cell-to-cell variations. Up until now, how this heterogeneity in chromatin conformation is shaped by chromatin condensation, TAD insulation, and transcription has remained mostly e...

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Detalles Bibliográficos
Autores principales: Götz, Markus, Messina, Olivier, Espinola, Sergio, Fiche, Jean-Bernard, Nollmann, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474875/
https://www.ncbi.nlm.nih.gov/pubmed/36104317
http://dx.doi.org/10.1038/s41467-022-32973-y