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Cytotoxic CD8(+) T cells may be drivers of tissue destruction in Sjögren’s syndrome

Sjögren’s syndrome is a chronic autoimmune disorder whose pathogenesis is poorly understood and that lacks effective therapies. Detailed quantitative and spatial analyses of tissues affected by Sjögren’s syndrome were undertaken, including the quantitation of the frequency of selected cell–cell inte...

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Detalles Bibliográficos
Autores principales: Kaneko, Naoki, Chen, Hu, Perugino, Cory A., Maehara, Takashi, Munemura, Ryusuke, Yokomizo, Shiho, Sameshima, Junsei, Diefenbach, Thomas J., Premo, Katherine R., Chinju, Akira, Miyahara, Yuka, Sakamoto, Mizuki, Moriyama, Masafumi, Stone, John H., Nakamura, Seiji, Pillai, Shiv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475031/
https://www.ncbi.nlm.nih.gov/pubmed/36104369
http://dx.doi.org/10.1038/s41598-022-19397-w