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Cytotoxic CD8(+) T cells may be drivers of tissue destruction in Sjögren’s syndrome
Sjögren’s syndrome is a chronic autoimmune disorder whose pathogenesis is poorly understood and that lacks effective therapies. Detailed quantitative and spatial analyses of tissues affected by Sjögren’s syndrome were undertaken, including the quantitation of the frequency of selected cell–cell inte...
Autores principales: | Kaneko, Naoki, Chen, Hu, Perugino, Cory A., Maehara, Takashi, Munemura, Ryusuke, Yokomizo, Shiho, Sameshima, Junsei, Diefenbach, Thomas J., Premo, Katherine R., Chinju, Akira, Miyahara, Yuka, Sakamoto, Mizuki, Moriyama, Masafumi, Stone, John H., Nakamura, Seiji, Pillai, Shiv |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475031/ https://www.ncbi.nlm.nih.gov/pubmed/36104369 http://dx.doi.org/10.1038/s41598-022-19397-w |
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