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Mild dyslipidemia accelerates tumorigenesis through expansion of Ly6C(hi) monocytes and differentiation to pro-angiogenic myeloid cells

Cancer and cardiovascular disease (CVD) share common risk factors such as dyslipidemia, obesity and inflammation. However, the role of pro-atherogenic environment and its associated low-grade inflammation in tumor progression remains underexplored. Here we show that feeding C57BL/6J mice with a non-...

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Detalles Bibliográficos
Autores principales: Tran, Thi, Lavillegrand, Jean-Remi, Lereverend, Cedric, Esposito, Bruno, Cartier, Lucille, Montabord, Melanie, Tran-Rajau, Jaouen, Diedisheim, Marc, Gruel, Nadège, Ouguerram, Khadija, Paolini, Lea, Lenoir, Olivia, Pinteaux, Emmanuel, Brabencova, Eva, Tanchot, Corinne, Urquia, Pauline, Lehmann-Che, Jacqueline, Le Naour, Richard, Merrouche, Yacine, Stockmann, Christian, Mallat, Ziad, Tedgui, Alain, Ait-Oufella, Hafid, Tartour, Eric, Potteaux, Stephane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475043/
https://www.ncbi.nlm.nih.gov/pubmed/36104342
http://dx.doi.org/10.1038/s41467-022-33034-0