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Nanoformulation improves antitumor efficacy of MAOI immune checkpoint blockade therapy without causing aggression-related side effects

MAOIs, a well-established class of antidepressant that operate through the inhibition of monoamine oxidase to increase available serotonin, have recently been identified as a surprisingly effective candidate for the circumvention of tumor-induced immune suppression due to their abilities to enhance...

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Detalles Bibliográficos
Autores principales: Brown, James, Li, Zhe, Wang, Xi, Kim, Yu Jeong, Wang, Yu-Chen, Zuo, Yanning, Hong, Weizhe, Wang, Pin, Li, Bo, Yang, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475110/
https://www.ncbi.nlm.nih.gov/pubmed/36120311
http://dx.doi.org/10.3389/fphar.2022.970324