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Genotyping of cerebrospinal fluid in lung cancer patients with leptomeningeal metastasis

BACKGROUND: The prognosis of non–small‐cell lung cancer (NSCLC) with leptomeningeal metastasis (LM) is poor. Detection of cell‐free DNA (cfDNA) by next generation sequencing (NGS) in cerebrospinal fluid (CSF) may facilitate diagnosis of LM and identification of drug resistance mechanisms, yet its cl...

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Detalles Bibliográficos
Autores principales: Nie, Naifu, Zhou, Haodong, Zhang, Kejun, liu, Lan, Luo, Nuo, Wang, Renyuan, Li, Xin, Zhu, Mengxiao, Hu, Chen, Wang, Yubo, Liu, Zhulin, Li, Li, He, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475227/
https://www.ncbi.nlm.nih.gov/pubmed/35896160
http://dx.doi.org/10.1111/1759-7714.14592