Large-Scale In Vitro and In Vivo CRISPR-Cas9 Knockout Screens Identify a 16-Gene Fitness Score for Improved Risk Assessment in Acute Myeloid Leukemia

PURPOSE: The molecular complexity of acute myeloid leukemia (AML) presents a considerable challenge to implementation of clinical genetic testing for accurate risk stratification. Identification of better biomarkers therefore remains a high priority to enable improving established stratification and...

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Detalles Bibliográficos
Autores principales: Jin, Peng, Jin, Qiqi, Wang, Xiaoling, Zhao, Ming, Dong, Fangyi, Jiang, Ge, Li, Zeyi, Shen, Jie, Zhang, Wei, Wu, Shishuang, Li, Ran, Zhang, Yunxiang, Li, Xiaoyang, Li, Junmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Precision Medicine and Imaging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475249/
https://www.ncbi.nlm.nih.gov/pubmed/35877119
http://dx.doi.org/10.1158/1078-0432.CCR-22-1618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475249/
https://www.ncbi.nlm.nih.gov/pubmed/35877119
http://dx.doi.org/10.1158/1078-0432.CCR-22-1618

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