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Induction of natural IgE by glucocorticoids

IgE mediates allergic responses by coating mast cell or basophil surfaces and inducing degranulation upon binding a specific allergen. IgE can also be spontaneously produced in the absence of foreign allergens; yet the origin, regulation, and functions of such “natural” IgE still remain largely unkn...

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Detalles Bibliográficos
Autores principales: Lim, Jaechul, Lin, Erica V., Hong, Jun Young, Vaidyanathan, Bharat, Erickson, Steven A., Annicelli, Charles, Medzhitov, Ruslan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475297/
https://www.ncbi.nlm.nih.gov/pubmed/36098746
http://dx.doi.org/10.1084/jem.20220903