Transit-amplifying cells control R-spondins in the mouse crypt to modulate intestinal stem cell proliferation

Intestinal epithelium regenerates rapidly through proliferation of intestinal stem cells (ISCs), orchestrated by potent mitogens secreted within the crypt niche. However, mechanisms regulating these mitogenic factors remain largely unknown. Here, we demonstrate that transit-amplifying (TA) cells, ma...

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Detalles Bibliográficos
Autores principales: Chaves-Pérez, Almudena, Santos-de-Frutos, Karla, de la Rosa, Sergio, Herranz-Montoya, Irene, Perna, Cristian, Djouder, Nabil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475298/
https://www.ncbi.nlm.nih.gov/pubmed/36098959
http://dx.doi.org/10.1084/jem.20212405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475298/
https://www.ncbi.nlm.nih.gov/pubmed/36098959
http://dx.doi.org/10.1084/jem.20212405

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