Association Between Adrenal-Restrictive HSD3B1 Inheritance and Hormone-Independent Subtypes of Endometrial and Breast Cancer

BACKGROUND: The germline variant rs1047303 (HSD3B1[1245A/C]), restricting or enabling production of potent androgens and estrogens from adrenal precursors, affects outcomes of castration-resistant prostate cancer and is associated with estrogen receptor positivity in postmenopausal breast cancer. Li...

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Detalles Bibliográficos
Autores principales: McManus, Jeffrey M, Vargas, Roberto, Bazeley, Peter S, Schumacher, Fredrick R, Sharifi, Nima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475354/
https://www.ncbi.nlm.nih.gov/pubmed/35947687
http://dx.doi.org/10.1093/jncics/pkac061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475354/
https://www.ncbi.nlm.nih.gov/pubmed/35947687
http://dx.doi.org/10.1093/jncics/pkac061

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