Combination of Metformin and Sorafenib Induces Ferroptosis of Hepatocellular Carcinoma Through p62-Keap1-Nrf2 Pathway

Hepatocellular carcinoma (HCC) is one of the most lethal cancers in the world. Sorafenib is the first small-molecule multi-kinase inhibitors approved by FDA for treatment of advanced HCC. Metformin has been demonstrated to have benefit for preventing cancer progression. In human recurrent HCCs, NF-E...

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Detalles Bibliográficos
Autores principales: Tang, Kezhong, Chen, Qing, Liu, Yanmo, Wang, Lantian, Lu, Wenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475364/
https://www.ncbi.nlm.nih.gov/pubmed/36118519
http://dx.doi.org/10.7150/jca.76618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475364/
https://www.ncbi.nlm.nih.gov/pubmed/36118519
http://dx.doi.org/10.7150/jca.76618

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