Comparison of hydrophobicity scales for predicting biophysical properties of antibodies

While antibody-based therapeutics have grown to be one of the major classes of novel medicines, some antibody development candidates face significant challenges regarding expression levels, solubility, as well as stability and aggregation, under physiological and storage conditions. A major determin...

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Detalles Bibliográficos
Autores principales: Waibl, Franz, Fernández-Quintero, Monica L., Wedl, Florian S., Kettenberger, Hubert, Georges, Guy, Liedl, Klaus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475378/
https://www.ncbi.nlm.nih.gov/pubmed/36120542
http://dx.doi.org/10.3389/fmolb.2022.960194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475378/
https://www.ncbi.nlm.nih.gov/pubmed/36120542
http://dx.doi.org/10.3389/fmolb.2022.960194

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