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Comparison of hydrophobicity scales for predicting biophysical properties of antibodies
While antibody-based therapeutics have grown to be one of the major classes of novel medicines, some antibody development candidates face significant challenges regarding expression levels, solubility, as well as stability and aggregation, under physiological and storage conditions. A major determin...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475378/ https://www.ncbi.nlm.nih.gov/pubmed/36120542 http://dx.doi.org/10.3389/fmolb.2022.960194 |