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Lgr5(+) cell fate regulation by coordination of metabolic nuclear receptors during liver repair
Background: Leucine-rich repeat-containing G protein-coupled receptor 5 (Lgr5) is a target gene of Wnt/β-Catenin which plays a vital role in hepatic development and regeneration. However, the regulation of Lgr5 gene and the fate of Lgr5(+) cells in hepatic physiology and pathology are little known....
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475469/ https://www.ncbi.nlm.nih.gov/pubmed/36168631 http://dx.doi.org/10.7150/thno.74194 |