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Lgr5(+) cell fate regulation by coordination of metabolic nuclear receptors during liver repair

Background: Leucine-rich repeat-containing G protein-coupled receptor 5 (Lgr5) is a target gene of Wnt/β-Catenin which plays a vital role in hepatic development and regeneration. However, the regulation of Lgr5 gene and the fate of Lgr5(+) cells in hepatic physiology and pathology are little known....

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Detalles Bibliográficos
Autores principales: Qin, Dan, Liu, Shenghui, Lu, Yuanyuan, Yan, Yi, Zhang, Jing, Cao, Shiyao, Chen, Mi, Chen, Ning, Huang, Wendong, Wang, Liqiang, Chen, Xiangmei, Zhang, Lisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475469/
https://www.ncbi.nlm.nih.gov/pubmed/36168631
http://dx.doi.org/10.7150/thno.74194

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