Acyl chain selection couples the consumption and synthesis of phosphoinositides

Phosphoinositides (PIPn) in mammalian tissues are enriched in the stearoyl/arachidonoyl acyl chain species (“C38:4”), but its functional significance is unclear. We have used metabolic tracers (isotopologues of inositol, glucose and water) to study PIPn synthesis in cell lines in which this enrichme...

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Detalles Bibliográficos
Autores principales: Barneda, David, Janardan, Vishnu, Niewczas, Izabella, Collins, Daniel M, Cosulich, Sabina, Clark, Jonathan, Stephens, Len R, Hawkins, Phillip T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475507/
https://www.ncbi.nlm.nih.gov/pubmed/35771169
http://dx.doi.org/10.15252/embj.2021110038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475507/
https://www.ncbi.nlm.nih.gov/pubmed/35771169
http://dx.doi.org/10.15252/embj.2021110038

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