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Acyl chain selection couples the consumption and synthesis of phosphoinositides
Phosphoinositides (PIPn) in mammalian tissues are enriched in the stearoyl/arachidonoyl acyl chain species (“C38:4”), but its functional significance is unclear. We have used metabolic tracers (isotopologues of inositol, glucose and water) to study PIPn synthesis in cell lines in which this enrichme...
Autores principales: | Barneda, David, Janardan, Vishnu, Niewczas, Izabella, Collins, Daniel M, Cosulich, Sabina, Clark, Jonathan, Stephens, Len R, Hawkins, Phillip T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475507/ https://www.ncbi.nlm.nih.gov/pubmed/35771169 http://dx.doi.org/10.15252/embj.2021110038 |
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