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Targeting Glutamine Metabolism to Enhance Immunoprevention of EGFR‐Driven Lung Cancer

Lung cancer is the leading cause of cancer death worldwide. Vaccination against EGFR can be one of the venues to prevent lung cancer. Blocking glutamine metabolism has been shown to improve anticancer immunity. Here, the authors report that JHU083, an orally active glutamine antagonist prodrug desig...

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Detalles Bibliográficos
Autores principales: Huang, Mofei, Xiong, Donghai, Pan, Jing, Zhang, Qi, Sei, Shizuko, Shoemaker, Robert H., Lubet, Ronald A., Montuenga, Luis M., Wang, Yian, Slusher, Barbara S., You, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475521/
https://www.ncbi.nlm.nih.gov/pubmed/35861366
http://dx.doi.org/10.1002/advs.202105885