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Small Activating RNA Modulation of the G Protein‐Coupled Receptor for Cancer Treatment

G protein‐coupled receptors (GPCRs) are the most common and important drug targets. However, >70% of GPCRs are undruggable or difficult to target using conventional chemical agonists/antagonists. Small nucleic acid molecules, which can sequence‐specifically modulate any gene, offer a unique oppor...

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Detalles Bibliográficos
Autores principales: Xiong, Yunfang, Ke, Ran, Zhang, Qingyu, Lan, Wenjun, Yuan, Wanjun, Chan, Karol Nga Ieng, Roussel, Tom, Jiang, Yifan, Wu, Jing, Liu, Shuai, Wong, Alice Sze Tsai, Shim, Joong Sup, Zhang, Xuanjun, Xie, Ruiyu, Dusetti, Nelson, Iovanna, Juan, Habib, Nagy, Peng, Ling, Lee, Leo Tsz On
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475523/
https://www.ncbi.nlm.nih.gov/pubmed/35712764
http://dx.doi.org/10.1002/advs.202200562