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Small Activating RNA Modulation of the G Protein‐Coupled Receptor for Cancer Treatment
G protein‐coupled receptors (GPCRs) are the most common and important drug targets. However, >70% of GPCRs are undruggable or difficult to target using conventional chemical agonists/antagonists. Small nucleic acid molecules, which can sequence‐specifically modulate any gene, offer a unique oppor...
Autores principales: | Xiong, Yunfang, Ke, Ran, Zhang, Qingyu, Lan, Wenjun, Yuan, Wanjun, Chan, Karol Nga Ieng, Roussel, Tom, Jiang, Yifan, Wu, Jing, Liu, Shuai, Wong, Alice Sze Tsai, Shim, Joong Sup, Zhang, Xuanjun, Xie, Ruiyu, Dusetti, Nelson, Iovanna, Juan, Habib, Nagy, Peng, Ling, Lee, Leo Tsz On |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475523/ https://www.ncbi.nlm.nih.gov/pubmed/35712764 http://dx.doi.org/10.1002/advs.202200562 |
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