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Tumor-associated macrophage-specific CD155 contributes to M2-phenotype transition, immunosuppression, and tumor progression in colorectal cancer

BACKGROUND: Onco-immunogenic molecule CD155 is overexpressed in various tumor microenvironments (TME) including in colorectal cancer (CRC). Tumor-associated macrophages (TAMs) are the most abundant immune cells in CRC TME and play a vital role in CRC progression and metastasis. Most studies have foc...

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Detalles Bibliográficos
Autores principales: Zhu, Xudong, Liang, Rongpu, Lan, Tianyun, Ding, Dongbing, Huang, Shengxin, Shao, Jun, Zheng, Zongheng, Chen, Tufeng, Huang, Yong, Liu, Jianpei, Pathak, Janak L, Wei, Hongbo, Wei, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476138/
https://www.ncbi.nlm.nih.gov/pubmed/36104099
http://dx.doi.org/10.1136/jitc-2021-004219