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Restoration of p53 activity via intracellular protein delivery sensitizes triple negative breast cancer to anti-PD-1 immunotherapy

BACKGROUND: Although immune checkpoint inhibitors (ICIs) have been shown to yield promising therapeutic outcomes in a small subset of patients with triple negative breast cancer (TNBC), the majority of patients either do not respond or subsequently develop resistance. Recent studies have revealed th...

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Detalles Bibliográficos
Autores principales: Yang, Zaofeng, Sun, Jacquelyne Ka-Li, Lee, Marianne M, Chan, Michael K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476161/
https://www.ncbi.nlm.nih.gov/pubmed/36104100
http://dx.doi.org/10.1136/jitc-2022-005068