KC-180-2 Exerts Anti-SCLC Effects via Dual Inhibition of Tubulin Polymerization and Src Signaling

[Image: see text] In this study, a series of N-benzyl-2-(5-phenylpyridin-2-yl) acetamide-based derivatives were successfully designed and synthesized as anti-cancer agents. KC-180-2 was screened as a potentially leading compound with dual mechanisms of action: Src signaling and tubulin polymerizatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Peng, Jian, Zeng, Yisheng, Hu, Xiaojun, Huang, Sheng, Gao, Xiaofang, Tian, Dong, Tian, Shuting, Qiu, Lan, Liu, Jin, Dong, Renhan, Zhan, Wei, Qin, Chuanjun, Guang, Bing, Yang, Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476193/
https://www.ncbi.nlm.nih.gov/pubmed/36120000
http://dx.doi.org/10.1021/acsomega.2c03408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476193/
https://www.ncbi.nlm.nih.gov/pubmed/36120000
http://dx.doi.org/10.1021/acsomega.2c03408

Ejemplares similares