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Posterior fossa ependymoma H3 K27-mutant: an integrated radiological and histomolecular tumor analysis

Posterior fossa group A ependymomas (EPN_PFA) are characterized by a loss of H3 K27 trimethylation due to either EZHIP overexpression or H3 p.K27M mutation, similar to H3 K27-altered diffuse midline gliomas (DMG), but in reverse proportions. Very little data is available in the literature concerning...

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Detalles Bibliográficos
Autores principales: Mariet, Cassandra, Castel, David, Grill, Jacques, Saffroy, Raphaël, Dangouloff-Ros, Volodia, Boddaert, Nathalie, Llamas-Guttierrez, Francisco, Chappé, Céline, Puget, Stéphanie, Hasty, Lauren, Chrétien, Fabrice, Métais, Alice, Varlet, Pascale, Tauziède-Espariat, Arnault
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476256/
https://www.ncbi.nlm.nih.gov/pubmed/36104744
http://dx.doi.org/10.1186/s40478-022-01442-4