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O-GlcNAcylation: an important post-translational modification and a potential therapeutic target for cancer therapy

O-linked β-d-N-acetylglucosamine (O-GlcNAc) is an important post-translational modification of serine or threonine residues on thousands of proteins in the nucleus and cytoplasm of all animals and plants. In eukaryotes, only two conserved enzymes are involved in this process. O-GlcNAc transferase is...

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Detalles Bibliográficos
Autores principales: Lu, Qingsong, Zhang, Xiaozhen, Liang, Tingbo, Bai, Xueli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476278/
https://www.ncbi.nlm.nih.gov/pubmed/36104770
http://dx.doi.org/10.1186/s10020-022-00544-y