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Captopril alleviates epilepsy and cognitive impairment by attenuation of C3-mediated inflammation and synaptic phagocytosis

Evidence from experimental and clinical studies implicates immuno-inflammatory responses as playing an important role in epilepsy-induced brain injury. Captopril, an angiotensin-converting enzyme inhibitor (ACEi), has previously been shown to suppress immuno-inflammatory responses in a variety of ne...

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Detalles Bibliográficos
Autores principales: Dong, Xinyan, Fan, Jianchen, Lin, Donghui, Wang, Xuehui, Kuang, Haoyu, Gong, Lifen, Chen, Chen, Jiang, Jie, Xia, Ningxiao, He, Dahong, Shen, Weida, Jiang, Peifang, Kuang, Rong, Zeng, Linghui, Xie, Yicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476304/
https://www.ncbi.nlm.nih.gov/pubmed/36104755
http://dx.doi.org/10.1186/s12974-022-02587-8