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Recent advances and limitations of mTOR inhibitors in the treatment of cancer

The PI3K-Akt-mechanistic (formerly mammalian) target of the rapamycin (mTOR) signaling pathway is important in a variety of biological activities, including cellular proliferation, survival, metabolism, autophagy, and immunity. Abnormal PI3K-Akt-mTOR signalling activation can promote transformation...

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Detalles Bibliográficos
Autores principales: Ali, Eunus S., Mitra, Kangkana, Akter, Shamima, Ramproshad, Sarker, Mondal, Banani, Khan, Ishaq N., Islam, Muhammad Torequl, Sharifi-Rad, Javad, Calina, Daniela, Cho, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476305/
https://www.ncbi.nlm.nih.gov/pubmed/36109789
http://dx.doi.org/10.1186/s12935-022-02706-8