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PEX5R/Trip8b-HCN2 channel regulating neuroinflammation involved in perioperative neurocognitive disorders

BACKGROUND: Clinical and animal studies demonstrated that neuroinflammation from anesthesia (sevoflurane) is the main contributor to cause perioperative neurocognitive disorders (PND). Recently, it was reported that microglia respond to hyperpolarization-activated cyclic nucleotide-gated (HCN) chann...

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Detalles Bibliográficos
Autores principales: Xu, Feng, Wang, Yafeng, Han, Linlin, Deng, Daling, Ding, Yuanyuan, Ma, LuLin, Zhang, Qingtong, Chen, Xiangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476339/
https://www.ncbi.nlm.nih.gov/pubmed/36104739
http://dx.doi.org/10.1186/s13578-022-00892-6