Cargando…
PEX5R/Trip8b-HCN2 channel regulating neuroinflammation involved in perioperative neurocognitive disorders
BACKGROUND: Clinical and animal studies demonstrated that neuroinflammation from anesthesia (sevoflurane) is the main contributor to cause perioperative neurocognitive disorders (PND). Recently, it was reported that microglia respond to hyperpolarization-activated cyclic nucleotide-gated (HCN) chann...
Autores principales: | Xu, Feng, Wang, Yafeng, Han, Linlin, Deng, Daling, Ding, Yuanyuan, Ma, LuLin, Zhang, Qingtong, Chen, Xiangdong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476339/ https://www.ncbi.nlm.nih.gov/pubmed/36104739 http://dx.doi.org/10.1186/s13578-022-00892-6 |
Ejemplares similares
-
Prolonged anesthesia induces neuroinflammation and complement-mediated microglial synaptic elimination involved in neurocognitive dysfunction and anxiety-like behaviors
por: Xu, Feng, et al.
Publicado: (2023) -
Characterization of the HCN Interaction Partner TRIP8b/PEX5R in the Intracardiac Nervous System of TRIP8b-Deficient and Wild-Type Mice
por: Scherschel, Katharina, et al.
Publicado: (2021) -
Modulation of thalamocortical oscillations by TRIP8b, an auxiliary subunit for HCN channels
por: Zobeiri, Mehrnoush, et al.
Publicado: (2017) -
Neuroinflammation and Perioperative Neurocognitive Disorders
por: Subramaniyan, Saraswathi, et al.
Publicado: (2019) -
Binding of the auxiliary subunit TRIP8b to HCN channels shifts the mode of action of cAMP
por: Hu, Lei, et al.
Publicado: (2013)