Total alkaloids of Sophora alopecuroides- and matrine-induced reactive oxygen species impair biofilm formation of Staphylococcus epidermidis and increase bacterial susceptibility to ciprofloxacin

OBJECTIVE: To investigate the mechanism by which total alkaloids of Sophora alopecuroides (TASA) and matrine (MT) impair biofilm to increase the susceptibility of Staphylococcus epidermidis (S. epidermidis) to ciprofloxacin. METHODS: The minimum biofilm inhibitory concentration (mBIC) was determined...

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Detalles Bibliográficos
Autores principales: Jia, Fang, Sun, Mei-yang, Zhang, Xiang-jun, Zhou, Xue-zhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476472/
https://www.ncbi.nlm.nih.gov/pubmed/36120175
http://dx.doi.org/10.1016/j.chmed.2020.02.006