Cargando…

Berberine exerts antidepressant-like effects via regulating miR-34a-synaptotagmin1/Bcl-2 axis

OBJECTIVE: Berberine, a cationic alkaloid first isolated in 1917, has been approved by the China Drug Administration for decades. Accumulating evidence demonstrated its antidepressant-like activities in vivo. Our previous study has shown that chronic stress leads to the upregulation of miR-34a in th...

Descripción completa

Detalles Bibliográficos
Autores principales: Yi, Li-tao, Zhu, Ji-xiao, Dong, Shu-qi, Chen, Min, Li, Cheng-fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476493/
https://www.ncbi.nlm.nih.gov/pubmed/36117760
http://dx.doi.org/10.1016/j.chmed.2020.11.001