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Berberine exerts antidepressant-like effects via regulating miR-34a-synaptotagmin1/Bcl-2 axis
OBJECTIVE: Berberine, a cationic alkaloid first isolated in 1917, has been approved by the China Drug Administration for decades. Accumulating evidence demonstrated its antidepressant-like activities in vivo. Our previous study has shown that chronic stress leads to the upregulation of miR-34a in th...
Autores principales: | Yi, Li-tao, Zhu, Ji-xiao, Dong, Shu-qi, Chen, Min, Li, Cheng-fu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476493/ https://www.ncbi.nlm.nih.gov/pubmed/36117760 http://dx.doi.org/10.1016/j.chmed.2020.11.001 |
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