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Functional and binding studies of gallic acid showing platelet aggregation inhibitory effect as a thrombin inhibitor

OBJECTIVE: This study was devoted to identifying natural thrombin inhibitors from traditional Chinese medicine (TCM) and evaluating its biological activity in vitro and binding characteristics. METHODS: A combination strategy containing molecular docking, thrombin inhibition assay, surface plasmon r...

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Detalles Bibliográficos
Autores principales: Zhang, Yuxin, Wang, Xing, Lu, Binan, Gao, Yanbin, Zhang, Yanling, Li, Yatong, Niu, Hongjuan, Fan, Lu, Pang, Zongran, Qiao, Yanjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476537/
https://www.ncbi.nlm.nih.gov/pubmed/36117662
http://dx.doi.org/10.1016/j.chmed.2021.09.001