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Functional and binding studies of gallic acid showing platelet aggregation inhibitory effect as a thrombin inhibitor
OBJECTIVE: This study was devoted to identifying natural thrombin inhibitors from traditional Chinese medicine (TCM) and evaluating its biological activity in vitro and binding characteristics. METHODS: A combination strategy containing molecular docking, thrombin inhibition assay, surface plasmon r...
Autores principales: | Zhang, Yuxin, Wang, Xing, Lu, Binan, Gao, Yanbin, Zhang, Yanling, Li, Yatong, Niu, Hongjuan, Fan, Lu, Pang, Zongran, Qiao, Yanjiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476537/ https://www.ncbi.nlm.nih.gov/pubmed/36117662 http://dx.doi.org/10.1016/j.chmed.2021.09.001 |
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